Spike can refer to a male name or a prickly object. As such, there are many characters and objects with this name.
- Spike: A green enemy from the Super Mario series, known to throw spiked balls at Mario.
- Spike Top: Another enemy from the Super Mario series, a Buzzy Beetle with a single spike on top of its shell.
- Foreman Spike: A grumpy foreman, an antagonist of Wrecking Crew.
- Spike Koopa: One of the fanmade Koopalings.
- Spike (Lakitu): Lakilester's adoptes son from Super Paper Bros.
- Spike Tyler: A supporting protagonist from HACKED.
- Spike (Brick 'n' Block): A pyramidal character from Brick 'n' Block.
- Spike The Porcupine (character): A porcupine character starring in a game of the same name.
- Spike The Porcupine Timeline: The series named after Spike The Porcupine.
- Spike Squad: The company behind Spike The Porcupine.
Characters with a similar name:
- Spikigi: A Spike with a red cap, appearing in Mario Party Aurora
- Spyke: A sea urchin-like character from Splatoon