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Renan: The Wrath of Dr. Mewtwo is the second movie of the anime, and is also the end of the second season of the anime.
After finishing creating the experiment "Dark End" that looks like Renan but with flopped big ears with two earrings on the left ear and sharp jaws, Dr. Mewtwo orders Dark End to elimate Renan and his friends. Will Renan suceed to stop Dark End and Dr. Mewtwo?
|Character||Japanese Voice Actor||English Voice Actor|
|Renario "Renan" Extreme||Miyu Irino||Brain Beacock|
|Dark End||Miyu Irino||Brain Beacock|
|Hiroshi the Quilava||MeJunko Takeuchi||Tara Jayne|
|Dr. Mewtwo||Masachika Ichimura||Steven Blum|
|Kenichi Suzumura||Crispin Freeman|
|Rexar the Croconaw||Kenyuu Horiuchi||Vic Mignogna|
|Estella the Espeon||Arisa Ogasawara||Michele Specht|