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This is the list of missions (also known as Jobs in some copies from the UK) in Grand Theft Auto: Life of Crime. There are several missions Mark can do from multiple characters and the reward are either an amount money or drugs. Missions are required to complete the storyline.
- My Beautiful Prison: Mark Smith, Jack Smith, and Rupert Smith escapes Demone Prison Island and creates a brutal jailbreak. Meanwhile, Rupert betrays Mark and is left for dead in the island of Flintwood.
- The Drug Deal: Mark and Jack begins another life of crime after escaping jail, so Mark starts drug dealing with dealers around Flintwood.
- No Tanks for the Memories: Jack is going to destroy the old abandoned eCola warehouse, so he orders Mark to steal a Rhino tank from the Fort 69 military base.
- Beware of the Bodyguard: Drug store owner Max Johnson, friend of Jack Smith, is going to do his afternoon errands, so he needs Mark to watch Get Wasted Drug Store.