Mario is walking along when Bowser attacks him. They fight but soon Dimentio comes and turns them all into blocks, and Bowser joins him. Mario and friends must make their way to Dimentio to save them! There are 50 Levels.
- Goomba Bloktoid: Destroys one Mario or good Bloktoid when touched.
- Shy Guy Bloktoid: Takes up too much space so you cannot connect Mario Bloktoids
- Fly Guy Bloktoid: Takes up space but moves around
- Bowser Bloktoid: Destroys Mario Bloktoids
- Bowser Jr. Bloktoid: Destroys Peach & Daisy Bloktoids
- Dimentio Bloktoid: Destroys Luigi Bloktoids
- Mario Bloktoid: Connect 20 to pass the level.
- Luigi Bloktoid: 1 Luigi has the equivlent of 2 Marios.
- Peach Bloktoid: These can eliminate Shy Guy Bloktoids.
- Daisy Bloktoid: These can eliminate Fly Guy Bloktoids.
- Wario Bloktoid: These, when touched by a Bad Bloktoid, spawn into different types of Bloktoids.
- Waluigi Bloktoid: These can eliminate All Bad Bloktoids.
- Yoshi Bloktoid: These can eliminate Bowser or Bowser Jr Bloktoids.
Bloktoiders (Playable Characters)
- Bowser (VS Mode)
- Bowser Jr. (VS Mode)
- Dimentio (VS Mode)
There is a VS Mode where players can compete, practice, or just plain play and have no Story Mode effect.